Translational Medicine in Hypertension Chair: Fernanda Consolim-Colombo

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1 August 11 8:45-9:00h Welcome Profª Maria Cristina Storópoli Introduction to the meeting 9:00-9:45h Conference I Eduardo Moacyr Krieger Translational Medicine in Hypertension Chair: Fernanda Consolim-Colombo Heart Rate Variability and Cardiovascular Diseases - Landmarks and perspectives Chair: Maria Claudia Irigayen Co- Chair: Luíz Aparecido Bortolotto 10:00-10:20h Presentation 1 Federico Aletti Critical analysis of the heat rate variability as a tool for studying ANS 10:20-10:40h Presentation 2 Adenauer Casalli Do physiological and pathological stresses produce different changes in heart variability? 10:40-11:00h Presentation 3 Kátia De Angelis Baroreflex sensitivity as a markers of a poor cardiovascular disease 11:00-11:20h Presentation 4 Ivani Trombetta Autonomic nervous system and exercise - perspectives in promoting cardiovascular health 11:20-11:40h Discussion 12:00-12:40h Special Lecture I Tomasz Guzik 12:40-13:00h Discussion Immune dysregulation on CV diseases: peripheral and central mechanisms Chair: Mario Fritsch 13:00-14:00h LUNCH

2 August 11 Neuro immunomodulation and cardiovascular disease Chair: Lisete Michelini Co-Chair: Kátia de Angelis 14:00-14:20h Presentation 5 Valdo José Dias The inflammatory Reflex - the new paradigm 14:20-14:40h Presentation 6 Rubens Fazan Baroreflex and neuro immunomodulation 14:40-15:00h Presentation 7 Mark Chapleau Immune-inflammatory mechanism in hypertension: from sympathovagal imbalance to end-organ damage 15:00-15:20 Presentation 8 Lisete Michelini Exercise training as a tool of immunomodulation in hypertension 15:20-15:40h Discussion 15:40-16:00h COFFE BREAK Contemporary issues in hypertension and target organ damage Chair: Francisco Laurindo Co-Chair: Rubens Fazan 16:00-16:20h Presentation 9 Kaushik Patel Nitric Oxide and Sympathetic activity in heart failure 16:20-16:40h Presentation 10 Francisco Laurindo Vascular NADPH oxidases: mechanisms of regulation on CV diseases 16:40-17:00h Presentation 11 Angelina Zanesco Blood pressure, gender and cardio-inflammatory mediators - a gap in the knowledge 17:00-17:20h Presentation 12 Edilamar Oliveira Role of MicroRNA in Hypertension 17:20-17:40h Discussion 17:50-18:20h Conference II Italo Biaggioni Orthostatic Hypotension: significance and management Chair: Carlos Penatti

3 August 12 9:00-9:30h Special Lecture II Kumar Rajesh 9:30-10:00h Special Lecture III Genevieve Nguyen New faces of renin angiotensin system Chair: Dulce Casarine Co-Chair: Heno F. Lopes Renin, prorenin, and Prorenin receptor Chair: Dulce Casarine Co-Chair: Heno F. Lopes Autonomic Homeostasis and Inflammation - the bases for cardiometabolic diseases Chair: Daniel Giannella Co-Chair: Cleber Camacho 10:20-10:40h Presentation 13 Heno Ferreira Lopes Metabolic Syndrome and sympathetic activity 10:40-11:00h Presentation 14 Luciano Drager Sleep disturbances and Inflammation 11:40-11:20h Presentation 15 Maria Lúcia Correa Gianella Molecular basis of cardiometabolic disease 11:20-11:40h Presentation 16 Mary Ann Flectcher Neuroimmune process, stress management and complex chronic ilness 11:40-12:00h Discussion

4 August 12 13:00-14:00h LUNCH 14:00-14:30 Conference III Ernesto Schiffrim Immune Mechanisms in Hypertension Chair: Mario Fritsch 14:30-16:00h Hands on Federico Aletti Registry and analysis of biological parameters in humans Cristiano Mostarda 14:30-16:00 Poster Presentation 16:00 Final remarks Fernanda Consolim Colombo

5 Ernesto Schiffrim Chair in Vascular and Hypertension ResearchMcGill University, Montreal, Quebec Canada Federico Aletti Dipartimento di Bioingegneria, Politecnico di Milano Italy Tomasz Guzik Jagiellonian University School of Medicine in Kraków Poland Mark Chapleau Internal Medicine, University of Iowa College of Medicine USA Kaushik P.Patel Department of Integrative Physiology, University of Nebrasca, Medical Center USA Kumar Rajesh Texas A&M Health Science Center College Of Medicine, Tx USA Genevieve Nguyen Centre for Interdisciplinary Research in Biology, Collège de France, Paris France Mary Ann Flectcher Institute for Neuro Immune Medicine, Nova Southeastern University, Fort Lauderdale, FL USA Italo Biaggioni Autonomic Dysfunction Center, Vanderbilt University School of Medicine, Nashville, TN USA Angelina Zanesco Departamento de Educação Física, UNESP Rio Claro / SP Edilamar Oliveira Escola de Educação Física e Esporte, USP SP Eduardo Moacyr Krieger Medicina Translacional, InCor-FMUSP; FAPESP SP Mario Saad Endocrinologia, Faculdade de Medicina, UNICAMP; FAPESP (a confirmar) Campinas / SP Ivani Trombetta PPG Medicina, Faculdade de Medicina, UNINOVE SP Rubens Fazan Departamento Fisiologia, Faculdade de Medicina USP Ribeirão Preto / SP Lisete Michelini Departamento Fisiologia, Instituto de Ciências Biomédicas- USP SP Kátia De Angelis PPG Medicina, Faculdade de Medicina, UNINOVE SP Heno Ferreira Lopes PPG Medicina, Faculdade de Medicina, UNINOVE SP Maria Lúcia Correa Gianella Faculdade de Medicina, USP SP Luciano Drager Unidade de Hipertensão, InCor-FMUSP SP Valdo Dias Departamento de Fisiologia, Universidade do Triângulo Mineiro Uberaba / MG Cristiano Mostarda Departamento de Fisiologia, Faculdade de Medicina, UF Maranhão São Luis / MA Faculty