Healthcare Information & Systems Opportunities for R&D João Paulo Silva Cunha José Maria Fernandes Ilídio Oliveira IEETA / Universidade de Aveiro www.ieeta.pt/sias jcunha@ieee.org Health Information Systems R&D Group@IEETA www.ieeta.pt/sias Coimbra - Jully 2008 2 1
20 anos de Telemedicina @ IEETA/UAveiro 1988 Primeira experiência de Telemedicina em Portugal (Ordem dos Engenheiros): Tele-EEG sobre linha analógica a 1200/2400 bps; Projecto EU 1FP AIM 1032 Telemedicine ; 1993 Sistema Tele-Radiologia sobre ISDN 64kbps Produto INTERACT - ATM Saúde 1996 Primeiro piloto Telemedicina cineangiografia coronária/ecocardiografia sobre fibra óptica ATM 8Mb/s cross EU Projecto EU HIM 1998 Contrato I&D CET/DID (PTinovação): Tele-consulta de ecocardiografia e ECG sobre multi-isdn 384kbps MediGraf PTelecom. 20 anos de Telemedicina @ IEETA/UAveiro 1999 Teleconsulta cine-angiografia coronária Gaia-Viseu sobre backbone óptico ATM 8Mb/s 2001 Tele-ecocardiografia Gaia-Maputo sobre link satelite ISDN 128kbps 2004 Vital Jacket Plataforma Vestível de Monitorização bio-sinais sobre banda móvel 3G 256 kbps; Hoje um produto Biodevices S.A. 2008 RNICF Rede Nac. Imagilogia Cerebral Funcional sobre fibra escura 1/10 Gbps (Brain Imaging Network BIN) 2
Projectos Europeus de Suporte 1988 Projecto EU Telemedicine AIM (1st FP) 1992 Proj. EU Esprit EDITH European Distributed Information Technology for Healthcare 1995 Proj EU Esprit special Action Hospital 2000 1996 Proj. EU Telematics HANSA - Healthcare Advanced Networks Systems Architecture 1996 Proj. EU Telematics HIM 1999 Proj. EU IST TEAM-HOS Best Team-work for Hospitals (Prime contractor) 2003 Proj. EU IST InfoGenMed Integrating genetic and medical information for health applications (Prime contractor) 2005 EU IST Excellence Network InfoBioMed (area coordinator) 2008 EU FP7 EELA-2 Grid infrastructure (Joint Research Unit) EGEE project - www.eu-egee.org Coimbra - Jully 2008 6 3
Brain imaging is multimodal = Lots of storage Clinical data MRI (T1, T2 etc.), CT fmri x minutes (5 min sequence typ.) EEG Video Eye tracker data It reaches 5Gb/hour in scanner 50 Gb/day; 500 Gb a month; 6Tb per year (30 Tb raw storage / year) Clinical Data fmri Coimbra - Jully 2008 7 Brain Imaging Network Grid (BING) BING is the IT infrastructure of RNICF Objectives Provide high speed IT infrastructure, storage and CPU Neuroscientist-friendly web portal (called BrainImaging.pt) Encourage scientific collaborations among participants Establish standards for multi-vendor, multimodal biomedical data exchange between participants Coimbra - Jully 2008 8 4
Portuguese Brain Imaging Network (BIN) BRAGA PORTO AVEIRO COIMBRA LISBOA Boarded in 2010 http://www.brainimaging.pt Portuguese Brain Imaging Network (BIN) BRAGA PORTO AVEIRO COIMBRA LISBOA Boarded in 2010 5
1/10Gbps link ~80 Tbytes storage 64 CPUs cluster BING multimedia Telemedicine workstation Gulbenkian - 29.07.2009 BING Multimedia Telemedicine Workstation BrainImaging.pt Portal Video conference In-bore video conference Gulbenkian - 29.07.2009 6
Gulbenkian - 29.07.2009 Playing neurosciences Brain ( or at least part of it) something (a.k.a. The model ) Human (or part of it) 7
Playing neurosciences Brain ( or at least part of it) something (a.k.a. The model ) Human (or part of it) What happens when a finger moves Finger motion from video fmri MRI Individual events EEG 8
Movement Quantification in Epilepsy Coimbra - Jully 2008 17 MovEpil 2D - Results Deg/sec. r 2 = 0.99 O Dwyer Silva Cunha et al., Young Invest. Award, Epilepsy Congress 2005, Paris O Dwyer Silva Cunha et al., Epilepsia 2007; 48: 524-530 9
Video-EEG-fMRI Video-EEG-fMRI Coimbra - Jully 2008 20 10
Clinical Support: Epilepsy surgery Take out what is bad EEG + ECOG + MRI + fmri + electric stimulation + sensorial stimulation + psycological protocols +... Keep what is working working - Speech, memory, motor function, Collaboration with HUC, Coimbra Brain Imaging: opportunities for MSc students Technical: How to do it? Video-EEG-fMRI: multimodal acquisition 3d Motion visualization and analysis IT framework, processing workflow, parallel computing playing neuroscience : What happens when I move the finger? What happens when I don t move the finger but think I m doing it? Potential application: Stroke or Parkinson s disease interhemispheric asymmetry study 11
From Lab to Certified Medical Product M-Health: Vital Responder Coimbra - Jully 2008 24 12
Vital Responder: 5 opportunities 1 Aquisition in mobile Data review 3 2 Team coordination and monitoring 13
Vital Responder: 5 opportunities Data Storage, managment and processing 4 5 Vital signs Position Accelarometers... More... VitalJacket extensions http://www.ieeta.pt/sias/ 14
Agradecimentos 15